PCOS and Fertility: 3 Evidence-Backed Truths You Need to Know

Polycystic Ovary Syndrome (PCOS) is one of the most common causes of fertility struggles, yet it’s also one of the most misunderstood. Around 1 in 10 women are affected (although newer research suggests may be up to 1 in 7), but the advice online often feels overwhelming, contradictory, or oversimplified.

As a GP who has also been through IVF and natural pregnancy, I’ve seen PCOS from both sides: as a doctor trained in the science, and as a patient living through the emotional and physical challenges. That dual perspective has shown me just how much nuance is missing in the standard conversations around PCOS and fertility.

Here are three evidence-backed truths that can make a real difference if you’re trying to conceive with PCOS.

1. PCOS isn’t one condition

Despite the name, PCOS isn’t a single disease — it’s a syndrome. That means it can present in different ways, with different underlying drivers. The four main subtypes include:

• Insulin-resistant PCOS (the most common)

• Inflammatory PCOS

• Adrenal PCOS

• Post-pill PCOS

Why does this matter? Because a “one-size-fits-all” approach won’t work. What helps one woman may do little for another, depending on the root cause. Personalised care, whether through lifestyle changes, medical support, or targeted supplements, is key.

2. It’s not just ovulation; egg quality matters too

When most people think about PCOS and fertility, they think about irregular ovulation. And it’s true: difficulty releasing an egg regularly is one of the main barriers to conceiving.

But there’s another layer that doesn’t get discussed enough: egg quality. PCOS can also impact how eggs develop, which affects their ability to fertilise and implant. That’s why the focus shouldn’t only be on restoring ovulation, but also on supporting the health and quality of the eggs themselves.

Understanding this shift is powerful. It changes the goal from simply “getting a period” to optimising reproductive health more holistically.

3. Inositol is one of the most researched supplements for PCOS

Inositol, a naturally occurring compound similar to B-vitamins, is one of the few supplements with strong research behind it for PCOS. Studies show it can:

• Improve insulin sensitivity

• Support regular ovulation

• Enhance egg quality

Not all formulations are equal, though. Evidence is strongest for myo-inositol combined with folic acid in specific ratios.

One trusted option is Inofolic, which contains this studied combination. It’s widely used in fertility care and has been evaluated in clinical studies.

Bringing it together

Managing PCOS-related fertility challenges isn’t about finding one “magic fix.” It’s about understanding the root drivers, supporting ovulation and egg quality, and using evidence-backed tools alongside medical and lifestyle care.

As someone who’s walked this path, both as a doctor and as a patient, I know how overwhelming the information can feel. My goal is to make it clear, practical, and grounded in evidence, so you can make confident decisions on your journey.